Regent Faculty

Dr. Stanley Saamoah Moffatt

Dr. Stanley Saamoah Moffatt

(Dean, School of Informatics & Engineering)


Contact:

Phone: 0242169839
Email: deansie@regentghana.net
Office: Rm 19, Kings Campus
Office Hours:

Primary Department: School of Informatics & Engineering

Education/Work Experience:


 

Brief Biography:

Dr. Moffatt is currently the Dean of the School of Informatics ad Engineering. Before joining Regent-Ghana in 2009, Dr. Moffatt was a senior researcher at the University of Texas and Assistant Professor at Florida Southeastern University in the United States, where he applied the principles of nanotechnology - engineering at a molecular level - to the design of a new class of nanotechnology-based therapeutics. His research interests include the development and application of shaped polymeric and fabricated nanomaterials for various biomaterials applications, including drug delivery and targeting, research of which incorporates several leading technology platforms including transcriptomics, proteomics, and bioinformatics.

Dr Moffatt is an astute and prolific researcher whose current research in Biomedical and Genetic Engineering hinges on the formulation and development of active macromolecular biological entities, particularly, nano-encapsulated polymeric particles for tumor delivery. Dr. Moffatt led a team in the United States in designing and developing a polymer-based therapeutics model involving a novel peptide linkage system for the tumor-specific molecule, CD13, which was published in several peer-reviewed international nanotechnology journals. Dr. Moffatt has made numerous presentations at various international meetings in the UK, USA and Asia in this interesting and dynamic area of research. As his contribution to the area of bio-nanotechnology in developing countries, Dr. Moffatt was recently appointed the Africa Coordinator for USEACANI (US-Europe-Asia Pacific- Caribbean Nanotechnology Initiative). He is married, a devoted christian and enjoys reading scientific literature.

 

Courses Teaching/Taught at Regent University:


 

Research/Scholarly Interests:

 

 

Memberships of Professional Bodies:

  1. American Association of Nanotechnology (USA)
  2. American Society for Gene Therapy (USA)
  3. American Association for Clinical Research (USA)
  4. Ghana Association of Biomedical Scientists (Ghana)

 

 

Recent Publications:

  1. Moffatt S, Wiehle S, and Cristiano R (2006). Uptake characteristics of NGR-coupled stealth PEI/pDNA nanoparticles loaded with PLGA-PEG-PLGA triblock copolymer for targeted delivery to human monocyte-derived dendritic cells Int. J. Pharm., 321:143-154.

  2. Moffatt S and Cristiano RJ (2006). A PEGylated J591 mAb loaded on PLGA-PEG-PLGA tri-block copolymer for targeted delivery: in vitro pharmacokinetic and pharmacodynamic evaluation in prostate cancer cells. Int. J. Pharm., 317 (1): 10-13.

  3. Moffatt S, Wiehle S and Cristiano RJ. (2006). A multifunctional PEI-based cationic polyplex for enhanced systemic p53-mediated gene therapy. Gene Ther 13 (21): 1512-1523.

  4. Moffatt S, Papasakelariou C, Wiehle S and Cristiano RJ. (2006). Successful in vivo immuno-targeting of prostate specific membrane antigen with a novel J591/PEI/DNA molecular conjugate. Gene Therapy 13 (9):761-772.

  5. Moffatt S, Wiehle S and Cristiano RJ (2005). Tumor specific gene delivery mediated by a novel peptide/polyethyeneimine/DNA polyplex targeting aminopeptidase N (CD13). Human Gene Therapy, 16: 57-67.

  6. Moffatt S and Mittal S. (2003). Biodistribution, pharmacological and toxicity studies of sodium alginate microspheres-carrying herpes simplex virus thymidine kinase gene with ganciclovir after intravenous administration in mice bearing subcutaneous tumors. FEMS Immunol. Med. Microbiol. PU, 28(2): 201-209.

  7. Moffatt S, Hayes, J. and Mittal, S. (2002). Sodium Alginate Microspheres as a Delivery Vehicle for Human Adenovirus- and Bovine adenovirus-Mediated Gene Therapy in adult BALB/c Mice. FEMS Immunol. Med. Microbiol. PU, 25(4):156-164.

  8. Suresh K. Mittal, Neeraj Aggarwal, G. Sailaja, Alberto van Olphen, Harm HogenEsch, Adam North, John Hays and Stanley Moffatt (2000). Immunization with DNA,adenovirus, or both in biodegradable alginate microspheres: effect of route of inoculation on immune response. Vaccine, 19: 253-263.

  9. Stanley Moffatt, John Hays, Harm HogenEsch and Suresh Mittal (2000).Circumvention of vector-specific neutralizing antibody response by alternating use of human and non-human adenoviruses: Implications in gene therapy. Virology. 272:159-167.

  10. Yaegashi N, Niinuma T, Chisaka H, Uehara S, Moffatt S, Tada K, Iwabuchi M, Matsunaga Y, Nakayama M, Yutani C, Osamura Y, Hirayama E, Okamura K, Sugamura K and Yajima A (1999). Parvovirus B19 infection induces apoptosis of erythroid cells in vitro and in vivo. J. Infect. 39:68-76.

  11. Yaegashi N, Niinuma T, Chisaka H, Uehara S, Okamura K, Shinkawa o, Tsunoda A, Moffatt S, Sugamura K and Yajima A (1999). Serologic study of human parvovirus B19 infection in pregnancy in Japan. J. Infect 38: 30-35.

  12. Yaegashi N, Niinuma T, Chisaka H, Watanabe T, Uehara S, Okamura K, Moffatt S, Sugamura K and Yajima A (1998). The Incidence of, and factors leading to, parvovirus B19-related hydrops fetalis following maternal infection: report of 10 cases and meta-analysis. J. Infect. 37: 28-35.

  13. Stanley Moffatt, Nobuo Yaegashi, Kohtaro Tada, Nobuyuki Tanaka and Kazuo Sugamura (1998). Human Parvovirus B19 Non-Structural (NS1) Protein Induces Apoptosis in Erythroid Lineage Cells. J. Virol., 72: 3018-3028.

  14. Oda Katsuhiko, Hironobu Asao, Masaya Higuchi, Stanley Moffatt, Masataka Nakamura, Koichi Tabayashi and Kazuo Sugamura (1997). Induction of IL-1?-converting enzyme-independent apoptosis by IL-2 in Human T cell Lines. Int. Jnl. Immunol. 9: 1303-1310.

  15. Stanley Moffatt, Nobuyuki Tanaka, Kohtaro Tada, Masato Nose, Masataka Nakamura, Osamu Muraoka, Toshio Hirano and Kazuo Sugamura (1996). A cytotoxic non-structural (NS1) protein of human parvovirus B19 induces activation of interleukin-6 gene expression. J. Virol., 70: 8485-8491.

 

 

Recent Conferences, Presentations etc:

Awards, Appointments, Promotions, Prizes & Fellowships:

Adverts/Links

 

 

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